Years ago I tried modding Fallout New Vegas and I think 4 on Fedora ages (I was running Fedora 28 at the time) ago using Mod Organizer 2 and it wouldn’t work for reasons I didn’t understand, possibly file system related. I’m thinking of switching to Pop! OS full time but I’d still like to play either modded Skyrim or FO4 from time to time, preferably using MO2.
it seems like it does but I didn’t tested, there is a part of the install script that adds a handler for nexus links but I opted to not install that part.