• Chee_Koala@lemmy.world
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    4 months ago

    Interesting find, apparently protein levels in spinal fluid vary pretty drastically after an aural migraine (where the pain comes after aura).

    They say the aura’s are a reaction to total neural activity shutdown, but I have never consciously experienced that before an aura. I would expect to have deja vu after such an event

    • Ranvier@sopuli.xyz
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      4 months ago

      Brain blackout is kind of a dramatic word. I’m pretty sure the article is trying to refer to cortical spreading depression.

      https://www.nature.com/articles/nrneurol.2013.192

      This is a wave of decreased activity going across the brain. It’s not the whole brain though, just a portion, and it tends to happen more often in the posterior brain than anterior. That’s why visual and other sensory auras (posterior brain) auras are more common than motor/weakness auras (anterior brain). The visual aura itself is the spreading wave of decreased activity going across the brain. It happens in primary visual cortex, primarily dealing with lines and colors. Visual space is represented radially on the brain, so it can often be circular. The “fortifications” or lines on the edges some people see come from the fact that it’s neurons that deal with line detection. Pain usually follows shortly after, but we aren’t exactly sure how that works, and this article was posing a possible mechanism to help link these. The main bulk of the visual aura where it’s grey, blurry, and indistinct is the decreased activity itself in the visual cortex. The area can get larger as the wave spreads.

      Deja vu or jamais vu have been reported with migraines, though that’s a very rare aura in comparison. It’s all depending on what parts of the brain are involved with the cortical spreading depression for that migraine aura for that person in terms of what symptom will happen. Deja vu would be more temporal lobe. Temporal lobe is the most common localization for focal epilepsies. So deja vu as a symptom of a neurologic disease would more commonly be seen with seizures (focal seizures are sometimes called auras too, which gets confusing but are inherently different from what is happening in a migraine). But don’t worry, most deja vu is nothing to worry about.

      • nilloc@discuss.tchncs.de
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        4 months ago

        This image is kinda similar to my experience. It starts as a very small spot, often just blocking a letter or 2 of a word I’m reading, then spreads out in an arc or rough circle.

        One interesting thing I’ve noticed as I get older (40s), is that if I’m moving over a distinct enough pattern, like a tile floor, the area inside the aura updates slower, or lags behind the surrounding (unaffected) area.

        Also as I’ve gotten older, the pain following the aura has thankfully gotten lows severe, and sometimes doesn’t happen.

        • Balder@lemmy.world
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          4 months ago

          In my experience the pain after the aura sometimes happens, sometimes not. But it’s usually not severe anyway, just an annoying constant headache that lasts for a while (hours) after that.

          • caseyweederman@lemmy.ca
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            4 months ago

            I get the feeling that it’s still happening to me, just outside my head. A floating migraine, tethered by tired spite.