“The body’s powerful immune system must be regulated, or it may attack our own organs. Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi made groundbreaking discoveries concerning peripheral immune tolerance that prevents the immune system from harming the body. Their discoveries have laid the foundation for a new field of research and spurred the development of new treatments, for example for cancer and autoimmune diseases.”

• The Nobel Foundation’s own report: https://www.nobelprize.org/prizes/medicine/2025/popular-information/
• Nature News’ report (may have soft paywall): https://www.nature.com/articles/d41586-025-03193-3
• Science News’ report (may have soft paywall): https://www.science.org/content/article/medicine-nobel-researchers-who-studied-how-body-polices-immune-system