I just use nextcloud as a target for backups (Aegis, Signal, QkSMS). Apps such as KeePassDX I have load the file via nextcloud. My contacts and calendar go through it as well, photos are just set to auto upload along with a few other directories.
As for the home screen layouts, I just take screenshots once I have it how I like and try to remember to take them again if I change stuff.
It’s not a full backup but I’m back up and running fairly quickly (Pixel 5A died on me 3 times in under a one year lifespan per device).
This is pretty great advice to get into it. I previously ran 3 poweredge 2950s but have since switched to nothing self hosted and back to everything self hosted but on a much leaner setup with a NUC and 14tb WD my book drive with a dual Noctua 4020 fan shroud I 3d printed that it absolutely needed as I killed the original drive in two weeks.
My replica is just a 14tb in my desktop I run rsync to pull the data occasionally after checking SMART status on the primary. It’s not versioned or perfect but it works great to give me a chance to backup my jellyfin media. Everything I care about also gets backed up via restic.
Eventually plan to run a build with the Modcase MASS with multiple drives but for now this setup has been working fantastic.