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If you look at the petapixel article, they complain about the speed (10mb/sec not 100) and have serious doubts about the reliability. Using this for backup or for security cameras sounds like a bad idea. It could still be good for some things like carrying your movie library on your phone, while still having a stable copy at home.
I used proxmox and have played a little with nix and guix, but simplest is just use debian, put /home on a separate logical partition from the system partition so you can reinstall the system without clobbering user files, and as people keep saying, backup early and often.