‘may’ is my most despised headline word. This article sounds like they may be onto something in mice trials anyway.

    • peopleproblems@lemmy.world
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      4 months ago

      No, but that’s essentially what Wegovy/Ozempic does. I’m pretty sure diarrhea is necessary for weight loss (it’s not).

      • theneverfox@pawb.social
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        4 months ago

        Nah, ozempic and Co change sugar absorption and satiation. People on it primarily eat way less instantly, apparently they just feel full and don’t feel any desire to keep going. It also slows sugar absorption which is why it helps manage diabetes, so that might also play some role

        So far we’ve found it thickens the intestinal lining and significantly messes with the reward pathways, we’re not sure what the long term effects could be. It seems like at best, you basically have to stay on it indefinitely or regain the weight (which is true of current weight loss drugs)

        • mojofrododojo@lemmy.world
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          4 months ago

          I have no doubt ads for ‘ozempic/watevgy class action lawsuits’ are in our future. anytime I see a drug take off like that I assume the side effects will be interesting.

        • peopleproblems@lemmy.world
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          4 months ago

          It certainly does mess with reward pathways, seems to counteract my antidepressant and Adderall.

          And yeah, I’m aware of the regain weight fun. My insurance currently has a lifetime cap of the benefit. So that will be interesting to see how that plays out. My hope is that the habits I’m forming stick, but I have doubts about that.

          Does the thickening of the intestinal wall contribute to the weird bowl changes? Seems like it either moves extremely fast or takes a week, no in between