• Spice Hoarder@lemmy.zip
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    8 hours ago

    Why do neurotypicals so desperately search for a cure/cause to autism?

    My boss talks about his kid like he’s some sort of miserable alien. I’m sure he’d like to rip the autism right out of them. How sad, he can’t just accept them for who they are.

  • SaveTheTuaHawk@lemmy.ca
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    1 day ago

    Oh fuck off funkee epidemiology with correlations. These clowns never get to mechanisms.

  • AItoothbrush@lemmy.zip
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    1 day ago

    Oh but sweety, thats inconvenient for governments so we’ll just ignore all studies pointing to that

  • WanderingThoughts@europe.pub
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    2 days ago

    Particle matter (PM2.5) is known to be a serious risk factor. The small particles are found in smoke and also pollution from cars. Living close to a highway also is a big risk factor for autism. So let’s deregulate pollution a big more and blame Tylenol and vaccines?

    • hanrahan@piefed.social
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      2 days ago

      People have been burning wood since time immemorial

      True and many millions die from it every year, most air pollution deaths are from woodsmoke, when we did it 10,000 years ago on the veld a fire was small and isolated and well ventilated,

      FF to modernty, climate change enhanced wildfire, billions of acres going up and a population of 9 billion, might be a concentration issue?

        • idiomaddict@lemmy.world
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          2 days ago

          People definitely tried to beat neurodivergence out of people. It doesn’t work, but it does make people mask more, which is a win for the kinds of people who beat children for being different

    • Mouselemming@sh.itjust.works
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      2 days ago

      The story says “wood smoke” but then they talk about Southern California wildfires, which typically contain a lot of other toxic materials from burning houses, other buildings, vehicles, power and telephone lines, etc. especially the fires burning in proximity to pregnant women.

        • prole@lemmy.blahaj.zone
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          1 day ago

          Bro, last year Altadena was completely and utterly destroyed. Tens of thousands of people’s houses burnt down.

          It’s getting worse every year with climate change

        • Mouselemming@sh.itjust.works
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          2 days ago

          In 2025 the Los Angeles wildfires burned more than 16,000 homes and other buildings. And about 6,300 cars.

          An outlier yes, but many of the wildfires do burn a significant number of structures, that’s the main reason firefighters engage with them. The purely chaparral fires (which may be allowed to burn) are more distant from most pregnant women so even though the smoke blows over it’s less concentrated.

        • hanrahan@piefed.social
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          2 days ago

          Perhaps you haven’t looked at wildfires ? , houses sheds and barns full of plastic, paints and farm chemicals, fields full of plastic used for weed suppression, vehicles and their tyres ignite and burn, including the metals etc

          Then the aftermath is that toxic shit going into water supplies next time it rains

  • finkrat@lemmy.world
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    2 days ago

    Cool can I level up my Autism if I go drive through Alberta during the summertime with the windows down?

  • daannii@lemmy.world
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    2 days ago

    Autism is caused by a lot of things that impact genes.

    But the biggest is the fathers age.

    Maybe young men should start storing their sperm at age 20 for when they decide if/when to have kids.

    As much as the mano sphere likes to say women are expired at 30. The truth is, in regards to fertility, we have perfect eggs our entire life.

    But male sperm declines fast. And not only that. Sperm count has decreased by like 50% or something in 50 years. Probably pollution.

    But I’m not here to say men expire at 25. Because men have more value than their sex cells , just like women.

    I am here to say that this knowledge could be used to reduce the risk of genetic errors and miscarriages.

    As much of a proponent I am for neurodivergent people, a large chunk of people with autism are not high functioning and have moderate to severe cognitive problems.

    Let’s try our best to bring healthy children into this world.

    • portifornia@piefed.social
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      1 day ago

      The truth is, in regards to fertility, we have perfect eggs our entire life.

      That is demonstrably false. While it’s true that oocytes have remarkable properties to maintain their proteins over long periods. And more-recent research suggests egg quality isn’t nearly the infertility culprit it was once thought to be (as compared to, ovarian health, for instance). The fact remains that as women age, chromosomal abnormalities DO occur at higher rates.

      • daannii@lemmy.world
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        1 day ago

        That’s not supported. Those errors are not significant until the woman is nearing 40 and after.

        At which point, most women are not having pregnancies.

        Also there is a specific error associated with eggs. It has to do with chromosome numbers. Is specific to disorders like downs syndrome and miscarriage. Called “aneuploidy”.

        https://scholar.google.com/scholar?as_ylo=2022&q=chromosome+errors+in+embryos+age+of+parents+&hl=en&as_sdt=0%2C14#d=gs_qabs&t=1771178714217&u=%23p%3DMnn8vjTVXIcJ Influence of parental age on chromosomal abnormalities in PGT-A embryos: exponentially increasing in the mother and completely null in the father

        Whereas sperm dna declines faster with age and is more prone to damage/changes from environmental factors like diet, exposure to chemicals, and the like.

        https://www.mdpi.com/2073-4425/14/2/486 Impact of Advanced Paternal Age on Fertility and Risks of Genetic Disorders in Offspring

        I suppose if someone was planning or at least considering the possibility of having biological children after age 35 (mother and/or father) then it would be realistic to save back sperm and egg from an earlier age to reduce multiple types of risk.

    • angrystego@lemmy.world
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      1 day ago

      I wonder what percent of the autism observed can be explained by the combined factors of father’s age and wildfires.

      • daannii@lemmy.world
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        19 hours ago

        That’s not how interaction statistics work.

        I don’t claim to be an expert on genetics.

        But there are experts out there researching these things.

        How different genes interact and change risk. How different genes interact with specific environment or exposures and create risk.

        There are scientific methods that are used to determine these things.

        But it’s not so easy to put out a single number that represents risk because of these complex interactions.

        The statistics are harder to understand, but when they are simplified they are less accurate/true.

      • daannii@lemmy.world
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        1 day ago

        This is well established. And has been for like 2 decades. https://www.thetransmitter.org/spectrum/link-parental-age-autism-explained/

        That’s why it’s crazy the GOP is like “Tylenol causes autism” and says that generally we don’t know what causes autism.

        Yes we do.

        We have for a long time.

        There is an insane amount of research on this. And still ongoing.

        Now that’s not to say it’s 100% fraternal. It’s not.

        Babies are born from a pairing of DNA.

        The relationship with mothers and autism is a lot more complex and the effect strength varies on a combination of many factors. It’s a bit simpler for fathers.

        Now before it sounds like I’m blaming sperm for all the human health problems I want to point out that nature designed sperm to be susceptible to fast DNA changes.

        Mutations are the way evolution occurs. Without one of the sex cells having the ability to change dna relatively “quickly”, the evolution changes of the organism may be too slow to adapt to new environments and may go extinct

        Everything is how it should be.

        But that doesn’t mean we can’t use modern medicine and science to help bring in healthier children.

        In the olden times when we were evolving into homo sapiens, life span was much shorter. Men weren’t typically fathering children in their 50s and 60s.

        The errors stack up.

    • Jax@sh.itjust.works
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      1 day ago

      The truth is, in regards to fertility, we have perfect eggs our entire life.

      Do you somehow have knowledge that disproves aneuploid eggs?

      Like, I don’t like the manosphere either, but that’s no reason to ignore science. That goes for them as well, considering that men are absolutely more likely to have mutations to their sperm factories considering… well, the nature of it.

      Edit: the answer is no, they do not have that knowledge. Meaning they’re full of themselves.

      • daannii@lemmy.world
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        1 day ago

        I should have said we have perfect DNA eggs during our pregnancy lifespan. I’m not sure how to phrase it. The age range of when average women have pregnancies. 20-35.

        Also the aneuploid egg thing is a very specific type of degrading. It more often results in miscarriages. Though sometimes children are born with a missing chromosome from this type of errors.

        • angrystego@lemmy.world
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          1 day ago

          Oh, so it doesn’t really disprove the manosphere woman expiration date… it’s more like both sexes are done around 30.

          • daannii@lemmy.world
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            19 hours ago

            Well neither sex is “expired” at 30. Because people have much higher value than their breeding potential.

            But in terms of passing on the best of yourself to your offspring, . Yeah there is a loss of quality over time.

            That quality loss might be higher in males (,because of sperm properties) but ultimately yes, it would be better to save eggs and sperm from an age before 30.

            I wouldn’t choose a partner based on how old they are though. There are much more important factors like if they would be a good parent.

    • foenkyfjutschah@programming.dev
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      1 day ago

      Let’s try our best to bring healthy children into this world.

      into a terminal ill ecosphere!

      btw, the correlation between autistic fathers’ age and autistic offspring is a social one. quiet obviously.

      • eleijeep@piefed.social
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        1 day ago

        btw, the correlation between autistic fathers’ age and autistic offspring is a social one. quiet obviously.

        Could you please explain, because it’s not obvious to me and if true that sounds like something I’d like to understand.

        • foenkyfjutschah@programming.dev
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          12 hours ago

          due to the difficulties with social interactions autistics do by average build the relationships that accomodate parenthood at a later age than other people.

          • eleijeep@piefed.social
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            10 hours ago

            So you’re saying that when looking for a correlation between age of the father and prevalence of autism of the child, you need to account for the confounding factor of heritability since among a population of fathers who are older, there will be a higher prevalence of autism than in a population of fathers of an even distribution of ages (the general population) due to the social factor.

            Sounds like a reasonable and logical take. Are you aware of any studies that show this or is it your own hypothesis?

  • EvilBit@lemmy.world
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    2 days ago

    If we ever invent a vaccine for wildfire smoke, shit’s gonna get crazy with MAGA.